Antifungal Activity of Petrolium and Ethanolic Extracts of Moringa Oleifera Leaves against Penicillium Chrysogenum and Cryptococcus Neoformans

Antifungal Activity of Petrolium and Ethanolic Extracts of Moringa Oleifera Leaves against Penicillium Chrysogenum and Cryptococcus Neoformans ( Vol-2,Issue-6,November - December 2017 )

Author: Kale Bhagwat, Dr. N. S. Mali, Lonkar Amar, Jadhav Sourabh

ijeab doi crossref DOI: 10.22161/ijeab/2.6.67

Keyword: Moringa oleifera, Cryptococcus neoformans, Antifungal , Antibacterial, Penicillium crysogenum.

Abstract: Moringa oleifera is well known medicinal plant. Its different parts are widely used for the treatment of different types of diseases since is have antibacterial and antifungal activity. The leaves are rich in iron, rhamnose and a unique group of compounds called glucosinolates and isothiocyanates. Other medical proprieties include antipyretic, antiepileptic, antiinflamatory, antiulcerative, antihypertensive, cholesterol lowering, antioxidant, anti diabetic. The current investigation was undertaken to evaluate the antifungal activities by petroleum ether and ethanolic extracts of Moringa oleifera leaves against Penicillium crysogenum and Cryptococcus neoformans. From our study, it is found that as concentration of Moringa leaves extract increases the diameter of zone of inhibition found increased. The results were higher and effective for ethanolic extract than petroleum extract. The result were also found more effective against Cryptococcus neoformans than Penicillium crysogenum.


[1] Nadkarni A. Indian Materia Medica. Popular Prakashan: Bombay, 1976, 810–6.
[2] Anwar F and Bhanger M. Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan. J. Agric. Food Chem. 2003,51:6558-63.
[3] Anwar F Moringa oleifera: a food plant with multiple medicinal uses. Phytother. Res. 2007,21:17-25.
[4] Morton JF. The horseradish tree, Moringa pterygosperma (Moringaceae)- A boon to arid lands? Econ. Bot.1991, 45:318-333.
[5] Gupta M. CNS activities of methanolic extract of Moringa oleifera root in mice. Fitoterapia 1999(3); 70: 244‐50.
[6] Shukla S Antifertility profile of the aqueous extract of Moringa oleifera roots. Journal of Ethnopharmacology 1998; 22(1): 51‐62.
[7] Lurling M and Beekman W. Anti‐cyanobacterial activity of Moringa oleifera seeds. Journal Appl Phycol 2010;22(4):503‐10.
[8] Fahey J The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry 2001; 56: 5–51.
[9] Bennett R et al. Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (Horseradish tree) and Moringa stenopetala L. J Agric Food Chem 2003;51: 3546–53.
[10] Pal S and Saha B. Studies on the antiulcer activity of M. oleifera leaf extract on gastric ulcer models in rats. Phytother. Res. 1995; 9: 463 – 5.
[11] Bukar A and Oyeyi T. Antimicrobal profile of Moringa oleifera Lam. Extracts against some food-borne microorganisms. Bayero Journal of Pure and Applied Sciences, 2010; 3(1): 43-8.
[12] Napolean, P Isolation, analysis and identification of phytochemicals of antimicrobial activity of Moringa oleifera Lam. Current Biotica, 2009; 3(1): 33 – 7.
[13] Nwosu M and Okafor J Preliminary studies on the antifungal activities of some medicinal plants against Basidiobolus and some other pathogenic fungi. Mycoses 1995; 38(5-6): 191-5.
[14] Chuang In vitro antifungal activity of ethanolic extract of the leaves of Moringa oleifera against dermatophytes. Bioresources Technology 2007; 98: 232–6.
[15] Srinivasan, D Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. Journal of Ethnopharmacology. 2001; 94: 217 - 22.
[16] Himal Paudel Chhetri et al. Phytochemical and antimicrobial evaluations of some medicinal plants of Nepal. Kathmandu university journal of science, engineering and technology september 2008; 49-54.

Cite this Article: Show All (MLA | APA | Chicago | Harvard | IEEE | Bibtex)

Total View: 54 Downloads: 10 Page No: 3303-3306