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Challenges and Solutions in D-Amino Acid Production Methods

Author(s): Magezi Joshua, Erum, Hero Nmeri Godspower, Samaila Boyi Ajeje, Minglong Shao, Zhina Qiao, Zhiming Rao

ijeab doi crossref DOI: 10.22161/ijeab.92.21

Abstract:
D-amino acids play a vital role in the pharmaceutical, food, and chemical industries for the manufacture of antibiotics, fertility drugs, sweeteners, and drugs against neural disorders. Examples include; they can be components in analgesics, antistress agents, antidiabetics (e.g., nateglinide), and anticoagulants. Therefore, industrial production of D amino acids is required, and owing to this, research has progressed while aiming towards improving yield and reducing the cost of production. However, to optimize large-scale production, challenges faced in currently used production methods must first be exposed for possible solutions. In this review, we provide a background of recent methods utilized, challenges in these methods, and solutions to enhance the production of D-amino acids.

Keywords:
D-amino acids, pharmaceutical industry, Industrial production, Production methods, Challenges and solutions

Article Info:
Received: 21 Feb 2024; Received in revised form: 01 Apr 2024; Accepted: 09 Apr 2024; Available online: 18 Apr 2024

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